Broad-range efficacy from new short-course regimens with ledipasvir/sofosbuvir in a single-tablet holds promise for treating persons infected with hepatitis C virus (HCV). Of the estimated 2.7 to 3.9 million Americans chronically infected with HCV, anywhere from 50% to 75% are undiagnosed and untreated. [1] Nearly half of infected persons report no exposure that would have put them at risk, …