Higher Body Weight Effect on Combined Hormonal Contraceptives

Given the growing number of reproductive-aged individuals with a BMI ≥ 30 kg/m2 the impact that weight might have on hormonal contraceptive efficacy is important for public health as well as for personal health. Although it does appear that obesity adversely affects contraceptive steroid hormone pharmacokinetics (e.g., drug levels and how drugs are metabolized), the literature has been conflicting regarding the impact on effectiveness. Shaalini Ramanadhan, MD, MCR, and Alison Edelman, MD, MPH, explored the issue for the 22nd edition of Contraceptive Technology.
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